Everyone knows Oprah and 50 Cent aren’t exactly buddies. In fact, they’ve been on opposite sides for a long time now, whether it’s personal issues or professional disagreements. During 50 Cent’s rise to fame, he wanted to prove he made it big by appearing on Oprah’s show.
This would have meant a lot for a guy from Jamaica Queens and also would have impressed his Oprah-loving grandmother. But when he suggested the idea to Oprah, she made it clear she wasn’t interested in his music or anything he had to offer.